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Capillary Electrophoresis Coupled To Mass Spectrometry for Forensic Analysis
Christian W. Huck, *
Verena Huck-Pezzei
Rania Bakry
Stefan Bachmann
Muhammad Najam-ul-Haq
Matthias Rainer
Günther K. Bonn
Authors Info & Affiliations
Verena Huck-Pezzei
Rania Bakry
Stefan Bachmann
Muhammad Najam-ul-Haq
Matthias Rainer
Günther K. Bonn
Authors Info & Affiliations
The Open Chemical Engineering Journal
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3 Nov 2007 •
RESEARCH ARTICLE
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DOI: 10.2174/1874123100701010030
Abstract
In this review the most important techniques, which are developed to hyphenate capillary electrophoresis to mass spectrometry (CE-MS), suitable for forensic analysis, are summarized. Analytes of interest are divided into four main parts, namely, compounds with amine containing side chains, compounds with N-containing saturated ring structures, other heterocycles and peptides. Sample pre-treatments and direct injection modes used in CE-MS for forensic analysis are briefly discussed from critical point of view. Special emphasis is placed to point out the advantages of mass spectrometric detection compared to UV- and laser- induced fluorescence (LIF) detections.
Keywords: Capillary electrophoresis, mass spectrometry, forensic, review, drugs.